Today's papers

· Edition No. 7

Lead Credibility: Promising Peer-reviewed PubMed abstract only

Pulling out small brain clots did not help stroke patients, and bleeding was more common

Using a thin tube to pull small blood clots out of the brain did not help stroke patients recover. In a trial of 244 people, 62% who had the procedure recovered well, versus 68% who got medicines alone.

Today's Pick Credibility: Promising Preprint bioRxiv abstract only

Brain's cleaning cells may pull the rubbish out of nerve cells, animal study hints

Brain immune cells called microglia pull bags of waste out of nerve cells. They bite off a tiny piece of the nerve cell's long arm and leave the rest intact, seen in lab dishes and in living animal brains.

  1. Credibility: Promising Preprint abstract only

    Fake medical trials cluster around a few repeat authors — one person wrote 104 of them

    Medical trials built on invented patient data mostly came from small groups that faked results again and again. Researchers examined 236 such withdrawn trials; a single author accounted for 104 of them.

  2. Credibility: Promising Preprint abstract only

    Menopause changes the mix of proteins in the blood, and some may be tied to brain aging

    After menopause, women's blood carries a different mix of proteins, many linked to inflammation and to brain aging. In four groups of older women, totalling 11,925, higher levels of these proteins went with weaker memory and thinking scores.

  3. Credibility: Promising Preprint abstract only

    Fly study hints that sperm proteins change fast to block cheating chromosomes

    In fruit flies, a protein that packs DNA tightly inside sperm keeps changing quickly. When scientists swapped in a related fly species' version, the daughter-making sperm packed badly, and the flies fathered mostly sons.

  1. Credibility: Early Preprint

    A robot that grows like a vine may one day listen for people trapped under rubble

    A soft tube robot that grows like a plant vine carried five microphones and worked out where a sound came from. In a quiet lab, curling it into a loop pinned down the sound's direction to within about 1 degree.

  1. Credibility: Promising abstract only

    Doing more of what you enjoy: a simple therapy for depression holds up across 105 trials

    Behavioral activation — a therapy that helps people slowly return to activities they find useful or enjoyable — clearly reduces depression. Researchers pooled 105 trials covering 13,933 patients and found a moderate-to-large benefit lasting up to a year.

  2. Credibility: Early Preprint abstract only

    Why one thing led to another: a hint that memory files stories by cause, not by clock

    After watching a TV show, people recalled events by cause and effect more than by time order. Brain scans showed a memory network switching back on for earlier events that caused later ones.